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A 3.5-nm Structure of Rat TRPV4 Cation Channel Revealed by Zernike Phase-contrast Cryoelectron Microscopy

The transient receptor potential vanilloid 4 (TRPV4) is a non-selective cation channel responsive to various stimuli including cell swelling, warm temperatures (27–35 °C), and chemical compounds such as phorbol ester derivatives. Here we report the three-dimensional structure of full-length rat TRPV...

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Autori principali: Shigematsu, Hideki, Sokabe, Takaaki, Danev, Radostin, Tominaga, Makoto, Nagayama, Kuniaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856998/
https://ncbi.nlm.nih.gov/pubmed/20044482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.090712
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