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Hsp90–Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore–microtubule binding sites

The formation of functional kinetochores requires the accurate assembly of a large number of protein complexes. The Hsp90–Sgt1 chaperone complex is important for this process; however, its targets are not conserved and its exact contribution to kinetochore assembly is unclear. Here, we show that hum...

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Detalhes bibliográficos
Main Authors: Davies, Alexander E., Kaplan, Kenneth B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856898/
https://ncbi.nlm.nih.gov/pubmed/20404110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200910036
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