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Aromatase is phosphorylated in situ at Serine-118
Phosphorylation of the cytochrome P450 aromatase has been proposed as a switch to rapidly modulate enzymatic activity and estrogen biosynthesis. Herein, we demonstrate that aromatase serine-118 is a potential phosphorylation site in mammalian cells. The amino acid context surrounding S118 is highly...
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Asıl Yazarlar: | , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2008
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856845/ https://ncbi.nlm.nih.gov/pubmed/18822378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2008.09.001 |
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