Aromatase is phosphorylated in situ at Serine-118

Phosphorylation of the cytochrome P450 aromatase has been proposed as a switch to rapidly modulate enzymatic activity and estrogen biosynthesis. Herein, we demonstrate that aromatase serine-118 is a potential phosphorylation site in mammalian cells. The amino acid context surrounding S118 is highly...

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Bibliografiske detaljer
Main Authors: Miller, Todd W., Shin, Incheol, Kagawa, Norio, Evans, Dean B., Waterman, Michael R., Arteaga, Carlos L.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856845/
https://ncbi.nlm.nih.gov/pubmed/18822378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2008.09.001
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