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A role of Histidine(151) in the lamprey Gonadotropin-Releasing Hormone Receptor (lGnRHR-1) : Functional insight of diverse amino acid residues in the position of Tyr of the DRY motif in GnRHR from an ancestral Type II receptor

The highly conserved DRY motif located at the end of the third transmembrane of G protein-coupled receptors has been described as a key motif for several aspects of GPCR functions. However, in the case of the vertebrate gonadotropin-releasing hormone receptor (GnRHR), the amino acid in the third pos...

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Detalhes bibliográficos
Main Authors: Kosugi, Takayoshi, Sower, Stacia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856804/
https://ncbi.nlm.nih.gov/pubmed/20005226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygcen.2009.12.001
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