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Monogenic IL-1 Mediated Autoinflammatory and Immunodeficiency Syndromes: Finding the Right Balance in Response to Danger Signals

INTRODUCTION: Interleukin -1 was the first cytokine identified and is a powerful inducer of fever and inflammation. The biologically active receptor for IL-1, shares signaling pathways with some pathogen recognition receptors, the toll like receptors (TLRs) which early on suggested an important role...

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Autors principals: Henderson, Cailin, Goldbach-Mansky, Raphaela
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856775/
https://ncbi.nlm.nih.gov/pubmed/20353899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.02.013
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