Anti-HIV-1 Activity of Weekly or Biweekly Treatment with Subcutaneous PRO 140, a CCR5 Monoclonal Antibody

BACKGROUND: PRO 140 is a humanized CCR5 monoclonal antibody that has demonstrated potent antiviral activity when administered intravenously to adults infected with CCR5-tropic (R5) human immunodeficiency virus type 1 (HIV-1). This study is the first to evaluate subcutaneous (SC) administration. METH...

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Detalhes bibliográficos
Main Authors: Jacobson, Jeffrey M., Thompson, Melanie A., Lalezari, Jacob P., Saag, Michael S., Zingman, Barry S., D’Ambrosio, Paul, Stambler, Nancy, Rotshteyn, Yakov, Marozsan, Andre J., Maddon, Paul J., Morris, Stephen A., Olson, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856743/
https://ncbi.nlm.nih.gov/pubmed/20377413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/652190
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