Detection of HIV-1 DNA resistance mutations by a sensitive assay at initiation of antiretroviral therapy is associated with virologic failure

BACKGROUND: Antiretroviral therapy (ART) has become more available throughout the developing world during the past five years. The World Health Organization recommends nonnucleoside reverse transcriptase inhibitor-based regimens as initial ART. However, their efficacy may be compromised by resistanc...

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Autori principali: Jourdain, Gonzague, Wagner, Thor Andrew, Ngo-Giang-Huong, Nicole, Sirungsi, Wasna, Klinbuayaem, Virat, Fregonese, Federica, Nantasen, Issaren, Techpornroong, Malee, Halue, Guttiga, Nilmanat, Ampaipith, Wittayapraparat, Pakorn, Chalermpolprapa, Veeradet, Pathipvanich, Panita, Yuthavisuthi, Prapap, Frenkel, Lisa M., Lallemant, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856716/
https://ncbi.nlm.nih.gov/pubmed/20377404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/652148
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