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Altered sphingolipid metabolism induced by tumor hypoxia -New vistas in glycolipid tumor markers

Uncontrolled growth of malignant cells produces hypoxic regions in locally advanced tumors. Recently we showed that tumor hypoxia-induced transcription of multiple genes involved in glycan synthesis, leading to expression of useful glycolipid tumor markers, such as gangliosides having N-glycolyl sia...

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Detalhes bibliográficos
Main Authors: Yin, Jun, Miyazaki, Keiko, Shaner, Rebecca L., Merrill, Alfred H., Kannagi, Reiji
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856702/
https://ncbi.nlm.nih.gov/pubmed/19913543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.11.019
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