A Defined and Xeno-Free Culture Method Enabling the Establishment of Clinical-Grade Human Embryonic, Induced Pluripotent and Adipose Stem Cells

BACKGROUND: The growth of stem cells in in vitro conditions requires optimal balance between signals mediating cell survival, proliferation, and self-renewal. For clinical application of stem cells, the use of completely defined conditions and elimination of all animal-derived materials from the est...

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Hauptverfasser: Rajala, Kristiina, Lindroos, Bettina, Hussein, Samer M., Lappalainen, Riikka S., Pekkanen-Mattila, Mari, Inzunza, Jose, Rozell, Björn, Miettinen, Susanna, Narkilahti, Susanna, Kerkelä, Erja, Aalto-Setälä, Katriina, Otonkoski, Timo, Suuronen, Riitta, Hovatta, Outi, Skottman, Heli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856688/
https://ncbi.nlm.nih.gov/pubmed/20419109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010246
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