Promoter polymorphism -119C/G in MYG1 (C12orf10) gene is related to vitiligo susceptibility and Arg4Gln affects mitochondrial entrance of Myg1

BACKGROUND: MYG1 (Melanocyte proliferating gene 1, also C12orf10 in human) is a ubiquitous nucleo-mitochondrial protein, involved in early developmental processes and in adult stress/illness conditions. We recently showed that MYG1 mRNA expression is elevated in the skin of vitiligo patients. Our ai...

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Détails bibliographiques
Auteurs principaux: Philips, Mari-Anne, Kingo, Külli, Karelson, Maire, Rätsep, Ranno, Aunin, Eerik, Reimann, Ene, Reemann, Paula, Porosaar, Orm, Vikeså, Jonas, Nielsen, Finn C, Vasar, Eero, Silm, Helgi, Kõks, Sulev
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856544/
https://ncbi.nlm.nih.gov/pubmed/20377893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-56
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