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Histone Deacetylase Inhibition Enhances Adenoviral Vector Transduction in Inner Ear Tissue

Adenovirus vectors (AdVs) are efficient tools for gene therapy in many tissues. Several studies have demonstrated successful transgene transduction with AdVs in the inner ear of rodents (Kawamoto et al., 2003). However, toxicity of AdVs (Morral et al., 2002) or lack of tropism to important cell type...

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Bibliografische gegevens
Hoofdauteurs: Taura, Akiko, Taura, Kojiro, Choung, Yun-Hoon, Masuda, Masatsugu, Pak, Kwang, Chavez, Eduardo, Ryan, Allen F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856459/
https://ncbi.nlm.nih.gov/pubmed/20060033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.12.064
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