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The Behavior of the Hydrophobic Effect under Pressure and Protein Denaturation

It is well known that proteins denature under high pressure. The mechanism that underlies such a process is still not clearly understood, however, giving way to controversial interpretations. Using molecular dynamics simulation on systems that may be regarded experimentally as limiting examples of t...

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Detalhes bibliográficos
Main Authors: Grigera, J. Raúl, McCarthy, Andres N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856145/
https://ncbi.nlm.nih.gov/pubmed/20409483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.12.4298
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