Tumor site-specific silencing of NF-κB p65 by targeted hollow gold nanospheres-mediated photothermal transfection

Nuclear factor-κB (NF-κB) transcription factor is a critical regulator of the expression of genes involved in tumor formation and progression. Successful RNA interference (RNAi) therapeutics targeting NF-κB is challenged by siRNA delivery systems, which can render targeted in vivo delivery, efficien...

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Bibliografiske detaljer
Main Authors: Lu, Wei, Zhang, Guodong, Zhang, Rui, Flores, Leo G, Huang, Qian, Gelovani, Juri G, Li, Chun
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856125/
https://ncbi.nlm.nih.gov/pubmed/20388791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3379
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