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Chemoinformatic Methods for Predicting Interference in Drug of Abuse/Toxicology Immnoassays

BACKGROUND: Immunoassays used for routine drug of abuse (DOA) and toxicology screening may be limited by cross-reacting compounds able to bind to the antibodies in a manner similar to the target molecule(s). To date, there has been little systematic investigation using computational tools to predict...

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Bibliografiske detaljer
Main Authors: Krasowski, Matthew D., Siam, Mohamed G., Iyer, Manisha, Pizon, Anthony F., Giannoutsos, Spiros, Ekins, Sean
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855823/
https://ncbi.nlm.nih.gov/pubmed/19342505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2008.118638
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