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Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation

Studies in mice have shown that CD70 on dendritic cells (DCs) is sufficient to convert T-cell tolerance into immunity and hence induce anti-tumour immune responses. Therefore, it is important to investigate (i) optimal stimuli to induce CD70 on human monocyte-derived DCs (MoDCs), which are widely us...

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Bibliografiske detaljer
Main Authors: Arimoto-Miyamoto, Kazue, Kadowaki, Norimitsu, Kitawaki, Toshio, Iwata, Satoshi, Morimoto, Chikao, Uchiyama, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855801/
https://ncbi.nlm.nih.gov/pubmed/20201989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03220.x
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