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p66(shc) Is Indispensable for Phenethyl Isothiocyanate-induced Apoptosis in Human Prostate Cancer Cells

Naturally-occurring phenethyl isothiocyanate (PEITC) selectively inhibits growth of cancer cells by causing apoptosis but the mechanism of cell death induction is not fully understood. We now demonstrate, for the first time, that growth factor adapter protein p66(shc) is indispensable for PEITC-indu...

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Autori principali: Xiao, Dong, Singh, Shivendra V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855757/
https://ncbi.nlm.nih.gov/pubmed/20354186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4451
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