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The actin-bundling protein L-plastin dissociates CCR7 proximal signaling from CCR7-induced motility
Chemokines promote lymphocyte motility by triggering F-actin rearrangements and inducing cellular polarization. Chemokines can also enhance cell-cell adhesion and co-stimulate T cells. Here we establish a requirement for the actin-bundling protein L-plastin (LPL) in CCR7- and S1P(1)-mediated T cell...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855624/ https://ncbi.nlm.nih.gov/pubmed/20194718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903851 |
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