N-Methyl-d-Aspartate and TrkB Receptors Protect Neurons Against Glutamate Excitotoxicity Through an Extracellular Signal-Regulated Kinase Pathway

N-Methyl-d-aspartate (NMDA) at a subtoxic concentration (100 μM) promotes neuronal survival against glutamate-mediated excitotoxicity via a brain-derived neurotrophic factor (BDNF) autocrine loop in cultured cerebellar granule cells. The signal transduction mechanism(s) underlying NMDA neuroprotecti...

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Main Authors: Zhu, Daming, Wu, Xuan, Strauss, Kenneth I., Lipsky, Robert H., Qureshi, Zehra, Terhakopian, Artin, Novelli, Antonello, Banaudha, Krishna, Marini, Ann M.
Format: Artigo
Jezik:Inglês
Izdano: 2005
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855499/
https://ncbi.nlm.nih.gov/pubmed/15744743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.20422
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