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Crumbs acts via the FERM-domain protein Expanded to regulate Salvador/Warts/Hippo signaling in Drosophila

BACKGROUND: Altered expression of apicobasal polarity factors is associated with cancer in vertebrates and tissue overgrowth in invertebrates, yet mechanisms by which these factors affect growth regulatory pathways are not well defined. We have tested the basis of an overgrowth phenotype driven by t...

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Autori principali: Robinson, Brian S., Huang, Juang, Hong, Yang, Moberg, Kenneth H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855393/
https://ncbi.nlm.nih.gov/pubmed/20362445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.03.019
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