Suppression of mRNAs Encoding Tegument Tetraspanins from Schistosoma mansoni Results in Impaired Tegument Turnover

Schistosomes express a family of integral membrane proteins, called tetraspanins (TSPs), in the outer surface membranes of the tegument. Two of these tetraspanins, Sm-TSP-1 and Sm-TSP-2, confer protection as vaccines in mice, and individuals who are naturally resistant to S. mansoni infection mount...

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Bibliographic Details
Main Authors: Tran, Mai H., Freitas, Tori C., Cooper, Leanne, Gaze, Soraya, Gatton, Michelle L., Jones, Malcolm K., Lovas, Erica, Pearce, Edward J., Loukas, Alex
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855321/
https://ncbi.nlm.nih.gov/pubmed/20419145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000840
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