Rapamycin Inhibits Postprandial-Mediated X-Box-Binding Protein-1 Splicing in Rat Liver

Recent studies have linked the unfolded protein response (UPR), in particular the inositol-requiring, endoplasmic reticulum-to-nucleus signaling protein 1α (IRE1α)-X-box-binding protein-1 (XBP1) branch of the UPR, to the regulation of lipogenesis and hepatic steatosis. In this study, we examined the...

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Hlavní autoři: Pfaffenbach, Kyle T., Nivala, Angela M., Reese, Lauren, Ellis, Flannery, Wang, Dong, Wei, Yuren, Pagliassotti, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Nutrition 2010
Témata:
Biochemical, Molecular, and Genetic Mechanisms
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855259/
https://ncbi.nlm.nih.gov/pubmed/20237065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.109.119883
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