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Mutant p53 disrupts the stress MAP kinase activation circuit induced by ASK1-dependent stabilization of Daxx
Daxx is a regulatory protein for apoptosis signal-regulating kinase 1 (ASK1) which activates Jun N-terminal kinase (JNK) and p38 pathways in response to stressors such as tumor necrosis factor α (TNFα). Here we show that TNFα treatment induces the accumulation of Daxx protein through ASK1 activation...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855193/ https://ncbi.nlm.nih.gov/pubmed/19789335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2133 |
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