Mutant p53 disrupts the stress MAP kinase activation circuit induced by ASK1-dependent stabilization of Daxx

Daxx is a regulatory protein for apoptosis signal-regulating kinase 1 (ASK1) which activates Jun N-terminal kinase (JNK) and p38 pathways in response to stressors such as tumor necrosis factor α (TNFα). Here we show that TNFα treatment induces the accumulation of Daxx protein through ASK1 activation...

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Hlavní autoři: Kitamura, Tetsuya, Fukuyo, Yayoi, Inoue, Masahiro, Horikoshi, Nobuko T, Shindoh, Masanobu, Rogers, Buck E., Usheva, Anny, Horikoshi, Nobuo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855193/
https://ncbi.nlm.nih.gov/pubmed/19789335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2133
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