Use of Biomarkers of Collagen Types I and III Fibrosis Metabolism to Detect Cardiovascular and Renal Disease in Chimpanzees (Pan troglodytes)

Cardiovascular disease is the leading cause of morbidity and mortality among captive chimpanzees. The most prevalent form of cardiovascular disease among chimpanzees is sudden cardiac death. Myocardial fibrosis was the only significant pathologic lesion observed in affected animals at necropsy. We p...

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Autores principales: Ely, John J, Bishop, Micah A, Lammey, Michael L, Sleeper, Meg M, Steiner, Jörg M, Lee, D Rick
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for Laboratory Animal Science 2010
Materias:
Nonhuman Primate Models
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855044/
https://ncbi.nlm.nih.gov/pubmed/20412692
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