Knockdown of Bicaudal C in Zebrafish (Danio rerio) Causes Cystic Kidneys: A Nonmammalian Model of Polycystic Kidney Disease

Polycystic kidney disease (PKD) is one of the leading causes of end-stage renal disease in humans and is characterized by progressive cyst formation, renal enlargement, and abnormal tubular development. Currently, there is no cure for PKD. Although a number of PKD genes have been identified, their p...

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Bibliographic Details
Main Authors: Bouvrette, Denise J, Sittaramane, Vinoth, Heidel, Jerry R, Chandrasekhar, Anand, Bryda, Elizabeth C
Format: Artigo
Language:Inglês
Published: American Association for Laboratory Animal Science 2010
Subjects:
Zebrafish Model
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855035/
https://ncbi.nlm.nih.gov/pubmed/20412683
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