MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate(1)(2)(3)

Background: The S-adenosylmethionine synthetase type 1 (MAT1A) gene encodes a key enzyme in one-carbon nutrient metabolism. Objective: This study aimed to determine the association of MAT1A variants with homocysteine, DNA damage, and cardiovascular disease (CVD). Design: Eight variants of MAT1A were...

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Detalhes bibliográficos
Main Authors: Lai, Chao-Qiang, Parnell, Laurence D, Troen, Aron M, Shen, Jian, Caouette, Heather, Warodomwichit, Daruneewan, Lee, Yu-Chi, Crott, Jimmy W, Qiu, Wei Qiao, Rosenberg, Irwin H, Tucker, Katherine L, Ordovás, José M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2010
Assuntos:
Gene-nutrient interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854908/
https://ncbi.nlm.nih.gov/pubmed/20335551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.2009.28923
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