A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth

Single-nucleotide polymorphisms (SNPs) in the regulatory regions of the genome can have a profound impact on phenotype. The G3072A polymorphism in intron 3 of insulin-like growth factor 2 (IGF2) is implicated in higher muscle content and reduced fat in European pigs and is bound by a putative repres...

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Main Authors: Butter, Falk, Kappei, Dennis, Buchholz, Frank, Vermeulen, Michiel, Mann, Matthias
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Scientific Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854606/
https://ncbi.nlm.nih.gov/pubmed/20134481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.6
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