Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced β2 integrin high-affinity state

We analyzed the involvement of Wiskott-Aldrich syndrome protein (WASp), a critical regulator of actin cytoskeleton remodeling, in the control of natural killer (NK)–cell migration. NK cells derived from patients with Wiskott-Aldrich syndrome/X-linked thrombocytopenia (WAS/XLT), carrying different mu...

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Detalhes bibliográficos
Main Authors: Stabile, Helena, Carlino, Claudia, Mazza, Cinzia, Giliani, Silvia, Morrone, Stefania, Notarangelo, Lucia D., Notarangelo, Luigi D., Santoni, Angela, Gismondi, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854428/
https://ncbi.nlm.nih.gov/pubmed/20130240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-235804
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