N(3)-o-toluyl-fluorouracil inhibits human hepatocellular carcinoma cell growth via sustained release of 5-FU

PURPOSE: N(3)-o-toluyl-fluorouracil (TFU), the prodrug of 5-fluorouracil (5-FU), is the metabolite of N(1)-acetyl-N(3)-o-toluyl-fluorouracil (atofluding). In the present study, we aimed to evaluate the efficacy of TFU on the inhibition of human hepatocellular carcinoma cells via sustained release of...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaofan, Zhong, Julia Li, Liu, Wei, Gao, Zuhua, Xue, Xia, Yue, Pan, Wang, Limei, Zhao, Cuirong, Xu, Wenfang, Qu, Xianjun
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854362/
https://ncbi.nlm.nih.gov/pubmed/19756602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1128-0
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