Systematic interpretation of molecular beacon PCR for identifying rpoB mutations in Mycobacterium tuberculosis isolates with mixed resistant and susceptible bacteria

Detection of multi-drug resistant tuberculosis (MDR-TB), a frequent cause of treatment failure, takes two or more weeks to identify by culture. Rifampicin (RIF) resistance is a hallmark of MDR-TB, and detection of mutations in the rpoB gene of Mycobacterium tuberculosis using molecular beacon probes...

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Hauptverfasser: Gomez, Diana I., Fisher-Hoch, Susan P., Bordt, Andrea S., Quitugua, Teresa N., Robledo, Jaime, Alvarez, Nataly, Correa, Nidia, McCormick, Joseph B., Restrepo, Blanca I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854294/
https://ncbi.nlm.nih.gov/pubmed/20227226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diagmicrobio.2009.12.007
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