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mTOR and cancer: many loops in one pathway

The mammalian target of rapamycin (mTOR) is a master regulator of cell growth and division that responds to a variety of stimuli, including nutrient, energy, and growth factors. In the last years, a significant number of pieces have been added to the puzzle of how mTOR coordinates and executes its f...

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Autores principales: Efeyan, Alejo, Sabatini, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854285/
https://ncbi.nlm.nih.gov/pubmed/19945836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2009.10.007
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