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Effect of ritonavir and atazanavir on human subcutaneous preadipocyte proliferation and differentiation

Protease inhibitors (PIs) have been implicated in the development of HIV-associated lipodystrophy through a reduction in the differentiation of preadipocytes. While atazanavir (ATV) is associated with fewer clinical metabolic abnormalities in the short-term, the effects of long-term exposure are not...

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Detalhes bibliográficos
Main Authors: Caso, Giuseppe, Mileva, Izolda, Mcnurlan, Margaret A, Mynarcik, Dennis C, Darras, Frank, Gelato, Marie C
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854271/
https://ncbi.nlm.nih.gov/pubmed/20153378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2010.02.004
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