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(R)-Roscovitine Prolongs the Mean Open Time of Unitary N-Type Calcium Channel Currents
(R)-roscovitine (Ros) is a cyclin-dependent kinase inhibitor that also has been shown to have direct agonist and antagonist actions on Ca(v)2.1 (P/Q-type) and Ca(v) 2.2 (N-type) families of voltage-gated calcium channels. These kinase-independent effects represent a novel opportunity to advance our...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854255/ https://ncbi.nlm.nih.gov/pubmed/20188151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.02.041 |
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