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Bone marrow lymphoid and myeloid progenitor cells are suppressed in 7,12-dimethylbenz(a)anthracene (DMBA) treated mice
In this study we used colony forming unit (CFU) assays to demonstrate rapid suppression (within 6 h) of lymphoid (CFU-preB) and myeloid (CFU-GM) progenitor cells in DMBA treated mice. The duration of these changes were consistent with the blood levels of DMBA and its metabolites that were achieved b...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854224/ https://ncbi.nlm.nih.gov/pubmed/20171256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2010.02.009 |
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