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Bone marrow lymphoid and myeloid progenitor cells are suppressed in 7,12-dimethylbenz(a)anthracene (DMBA) treated mice

In this study we used colony forming unit (CFU) assays to demonstrate rapid suppression (within 6 h) of lymphoid (CFU-preB) and myeloid (CFU-GM) progenitor cells in DMBA treated mice. The duration of these changes were consistent with the blood levels of DMBA and its metabolites that were achieved b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: N'jai, AU, Larsen, M, Shi, L, Jefcoate, CR, Czuprynski, CJ
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854224/
https://ncbi.nlm.nih.gov/pubmed/20171256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2010.02.009
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