Metabotropic Glutamate Receptor 5 Activity in the Nucleus Accumbens Is Required for the Maintenance of Ethanol Self-Administration in a Rat Genetic Model of High Alcohol Intake

BACKGROUND: Systemic modulation of Group I and II metabotropic glutamate receptors (mGluRs) regulate ethanol self-administration in a variety of animal models. Although these receptors are expressed in reward-related brain regions, the anatomical specificity of their functional involvement in ethano...

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Bibliografiske detaljer
Main Authors: Besheer, Joyce, Grondin, Julie J.M., Cannady, Reginald, Sharko, Amanda C., Faccidomo, Sara, Hodge, Clyde W.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854174/
https://ncbi.nlm.nih.gov/pubmed/19897175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2009.09.016
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