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Recombineering Hunchback identifies two conserved domains required to maintain neuroblast competence and specify early-born neuronal identity

The Hunchback/Ikaros family of zinc-finger transcription factors is essential for specifying the anterior/posterior body axis in insects, the fate of early-born pioneer neurons in Drosophila, and for retinal and immune development in mammals. Hunchback/Ikaros proteins can directly activate or repres...

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Autors principals: Tran, Khoa D., Miller, Michael R., Doe, Chris Q.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853844/
https://ncbi.nlm.nih.gov/pubmed/20335359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.048678
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