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Sirolimus and everolimus clearance in maintenance kidney and liver transplant recipients: Diagnostic efficiency of the concentration/dose ratio for the prediction of trough steady-state concentrations

OBJECTIVES: Therapeutic monitoring of sirolimus and everolimus is necessary in order to minimize adverse side-effects and to ensure effective immunosuppression. A sirolimus-dosing model using the concentration/dose ratio has been previously proposed for kidney transplant patients, and the aim of our...

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Detalhes bibliográficos
Main Authors: Bouzas, Lorena, Hermida, Jesús, Tutor, J. Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Informa Healthcare 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853790/
https://ncbi.nlm.nih.gov/pubmed/19943816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03009730903291026
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