A Phase II Study of Dasatinib in Patients with Chemo-sensitive Relapsed Small Cell Lung Cancer (CALGB 30602)

INTRODUCTION: SRC is an oncogene with an essential role in the invasiveness and metastasis of solid tumors including small cell lung cancer (SCLC). Dasatinib is a potent inhibitor of SRC as well as other tyrosine kinases. The primary objective of this study was to determine the efficacy of second-li...

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Главные авторы: Miller, Antonius A., Pang, Herbert, Hodgson, Lydia, Ramnath, Nithya, Otterson, Gregory A., Kelley, Michael J., Kratzke, Robert A., Vokes, Everett E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853764/
https://ncbi.nlm.nih.gov/pubmed/20087228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181cee36e
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