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BMPER is upregulated by statins and modulates endothelial inflammation by ICAM-1

OBJECTIVE: Besides cholesterol lowering statins exert pleiotropic effects on endothelial cells. Bone morphogenetic proteins (BMPs) have recently been implicated in vascular inflammation and disease. We set out to investigate the effect of statins on BMPER, a novel member of the BMP pathway. METHODS...

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Detalhes bibliográficos
Main Authors: Helbing, Thomas, Rothweiler, René, Heinke, Jennifer, Goetz, Lena, Diehl, Philipp, Zirlik, Andreas, Patterson, Cam, Bode, Christoph, Moser, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853692/
https://ncbi.nlm.nih.gov/pubmed/20042706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.201087
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