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Axin2 Regulates Chondrocyte Maturation and Axial Skeletal Development

Axis inhibition proteins 1 and 2 (Axin1 and Axin2) are scaffolding proteins that modulate at least two signaling pathways that are crucial in skeletogenesis: the Wnt/β-catenin and TGF-β signaling pathways. To determine whether Axin2 is important in skeletogenesis, we examined the skeletal phenotype...

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Autors principals: Dao, Debbie Y., Yang, Xue, Flick, Lisa M., Chen, Di, Hilton, Matthew J., O’Keefe, Regis J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853598/
https://ncbi.nlm.nih.gov/pubmed/19623616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.20954
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