Robust Generation of Oligodendrocyte Progenitors from Human Neural Stem Cells and Engraftment in Experimental Demyelination Models in Mice

BACKGROUND: Cell–based therapy holds great promises for demyelinating diseases. Human-derived fetal and adult oligodendrocyte progenitors (OPC) gave encouraging results in experimental models of dysmyelination but their limited proliferation in vitro and their potential immunogenicity might restrict...

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Main Authors: Neri, Margherita, Maderna, Claudio, Ferrari, Daniela, Cavazzin, Chiara, Vescovi, Angelo L., Gritti, Angela
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853578/
https://ncbi.nlm.nih.gov/pubmed/20405042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010145
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