MVL-PLA2, a Snake Venom Phospholipase A2, Inhibits Angiogenesis through an Increase in Microtubule Dynamics and Disorganization of Focal Adhesions

Integrins are essential protagonists of the complex multi-step process of angiogenesis that has now become a major target for the development of anticancer therapies. We recently reported and characterized that MVL-PLA2, a novel phospholipase A2 from Macrovipera lebetina venom, exhibited anti-integr...

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Detalhes bibliográficos
Main Authors: Bazaa, Amine, Pasquier, Eddy, Defilles, Céline, Limam, Ines, Kessentini-Zouari, Raoudha, Kallech-Ziri, Olfa, Battari, Assou El, Braguer, Diane, Ayeb, Mohamed El, Marrakchi, Naziha, Luis, José
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853567/
https://ncbi.nlm.nih.gov/pubmed/20405031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010124
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