A metabolomics approach using juvenile cystic mice to identify urinary biomarkers and altered pathways in polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease and affects 1 in 1,000 individuals. Ultrasound is most often used to diagnose ADPKD; such a modality is only useful late in the disease after macroscopic cysts are present. There is accumulating evidence...

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Main Authors: Taylor, Sandra L., Ganti, Sheila, Bukanov, Nikolay O., Chapman, Arlene, Fiehn, Oliver, Osier, Michael, Kim, Kyoungmi, Weiss, Robert H.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853321/
https://ncbi.nlm.nih.gov/pubmed/20130118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00722.2009
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