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Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction

In this study, we examined chronic norepinephrine suppression of insulin secretion in sheep fetuses with placental insufficiency-induced intrauterine growth restriction (IUGR). Glucose-stimulated insulin secretion (GSIS) was measured with a square-wave hyperglycemic clamp in the presence or absence...

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Bibliografische gegevens
Hoofdauteurs: Leos, Rafael A., Anderson, Miranda J., Chen, Xiaochuan, Pugmire, Juliana, Anderson, K. Arbor, Limesand, Sean W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853210/
https://ncbi.nlm.nih.gov/pubmed/20086198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00494.2009
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