Effects of substitution of Cx43 by Cx32 on myocardial energy metabolism, tolerance to ischaemia and preconditioning protection

Connexin 43 (Cx43) plays an important role in cardioprotective signalling by mechanisms at least in part independent of gap junctional communication. To investigate whether this role is related to specific properties of this connexin isoform, we used a knock-in mouse model in which the coding region...

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Main Authors: Rodríguez-Sinovas, Antonio, Sánchez, Jose A, González-Loyola, Alejandra, Barba, Ignasi, Morente, Miriam, Aguilar, Rio, Agulló, Esperanza, Miró-Casas, Elisatet, Esquerda, Neus, Ruiz-Meana, Marisol, García-Dorado, David
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2010
Fag:
Cardiovascular
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853001/
https://ncbi.nlm.nih.gov/pubmed/20156849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.186577
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