Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity

Intestinal barrier function is reduced in inflammatory bowel disease (IBD). Tumor necrosis factor (TNF) and interleukin (IL)-13, which are up-regulated in IBD, induce barrier defects that are associated with myosin light chain kinase (MLCK) activation and increased claudin-2 expression, respectively...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Weber, Christopher R., Raleigh, David R., Su, Liping, Shen, Le, Sullivan, Erika A., Wang, Yingmin, Turner, Jerrold R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852941/
https://ncbi.nlm.nih.gov/pubmed/20177070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.064808
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados