Sumoylation and the Structural Maintenance of Chromosomes (Smc) 5/6 Complex Slow Senescence through Recombination Intermediate Resolution

Telomeres are repetitive nucleoprotein structures that cap the ends of chromosomes. Without telomerase, telomeres shorten with replication and eventually signal cell cycle arrest (cell senescence). Homologous recombination (HR)-based mechanisms slow senescence, and distinct HR mechanisms support the...

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Hlavní autoři: Chavez, Alejandro, George, Vanessa, Agrawal, Vishesh, Johnson, F. Brad
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
DNA and Chromosomes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852929/
https://ncbi.nlm.nih.gov/pubmed/20159973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041277
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