Epigenetic Repression of PDZ-LIM Domain-containing Protein 2: IMPLICATIONS FOR THE BIOLOGY AND TREATMENT OF BREAST CANCER

The NF-κB transcription factor plays a pivotal role in breast cancer progression and therapy resistance. However, the mechanisms by which the tightly regulated NF-κB becomes constitutively activated during breast cancer pathogenesis remain obscure. Here, we report that PDZ-LIM domain-containing prot...

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Main Authors: Qu, Zhaoxia, Fu, Jing, Yan, Pengrong, Hu, Jing, Cheng, Shi-Yuan, Xiao, Gutian
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852914/
https://ncbi.nlm.nih.gov/pubmed/20185823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.086561
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