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Targeting TLR/IL-1R Signalling in Human Diseases

The members of Toll-like receptor/Interleukin (IL)-1 receptor (TLR/IL-1R) superfamily play a fundamental role in the immune response. These receptors detect microbial components and trigger complex signalling pathways that result in increased expression of multiple inflammatory genes. On the other h...

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Autori principali: Loiarro, Maria, Ruggiero, Vito, Sette, Claudio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852602/
https://ncbi.nlm.nih.gov/pubmed/20396389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/674363
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