Microbial alkaloid staurosporine induces formation of nanometer-wide membrane tubular extensions (cytonemes, membrane tethers) in human neutrophils

In the present work, we demonstrate that microbial alkaloid staurosporine (STS) and Ro 31-8220, structurally related to STS protein kinase C inhibitor, caused development of membrane tubular extensions in human neutrophils upon adhesion to fibronectin-coated substrata. STS-induced tubular extensions...

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Detalhes bibliográficos
Main Authors: Galkina, Svetlana I, Stadnichuk, Vladimir, Molotkovsky, Julian G, Romanova, Julia M, Sud’ina, Galina F, Klein, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852555/
https://ncbi.nlm.nih.gov/pubmed/20009568
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